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Generic Name Beclomethasone dipropionate DrugBank Accession Number DB00394 Background. Beclomethasone dipropionate is a second-generation synthetic corticosteroid agent [A179842] and a diester of beclomethasone, which is structurally similar to dexamethasone. 10 It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) 1 which …
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Generic Name Formoterol DrugBank Accession Number DB00983 Background. Formoterol is an inhaled beta 2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. 10 It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S) …
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Generic Name Fentanyl DrugBank Accession Number DB00813 Background. Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. 8 Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia. Label,15,16,17,18,19,20,21 Fentanyl is related to other opioids like morphine and …
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Updated: 8 hours ago
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Generic Name Minoxidil DrugBank Accession Number DB00350 Background. A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
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Updated: 6 hours ago
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Generic Name Omeprazole DrugBank Accession Number DB00338 Background. Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders.These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric …
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Absorption. Oral hydrocortisone at a dose of 0.2-0.3mg/kg/day reached a mean C max of 32.69nmol/L with a mean AUC of 90.63h*nmol/L 1 A 0.4-0.6mg/kg/day dose reached a mean C max of 70.81nmol/L with a mean AUC of 199.11h*nmol/L. 1 However, the pharmacokinetics of hydrocortisone can vary by 10 times from patient to patient. 1. Topical hydrocortisone cream is …
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Updated: 7 hours ago
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Generic Name Buprenorphine DrugBank Accession Number DB00921 Background. Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain. 12,15 It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. 19,20 Buprenorphine is commercially available as …
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Updated: 6 hours ago
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Generic Name Misoprostol DrugBank Accession Number DB00929 Background. Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. 13,14,4,2,10 The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while …
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Updated: 7 hours ago
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Generic Name Sodium chloride DrugBank Accession Number DB09153 Background. Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
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Updated: 3 hours ago
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Drug Interaction Checker. DrugBank contains the drug-drug interactions contained in the DrugBank database. This interaction checker is not intended as a substitute for professional medical advice, diagnosis, or treatment.