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Then, follow the previously mentioned quilt facing tutorial to attach the binding strips to the front side of the quilt on top of the prairie points. When the binding is pulled to the back, the points will extend out from the quilt top. You can see how color placement and staggering the points can put a whole new spin on prairie points.
RBPs typically bind to their targets via one or more RNA binding domains (RBDs) which are thought to have specific binding motifs ( Lunde et al., 2007 ). Due to the large number of known and predicted RBPs and their important role in RNA regulation, there has been much interest in systematically understanding their behavior.
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The PROTAC molecule specifically recognizes and binds to the target protein through the target protein ligand (POI Ligand) at one end and the E3 Ligase through the E3 Ubiquitin Ligase Ligand (E3 Ligase Ligand) at the other end.